Proteomic analysis of human follicular fluid from fertile women
نویسندگان
چکیده
منابع مشابه
Comparative Proteomic Analysis of Yak Follicular Fluid during Estrus
The breeding of yaks is highly seasonal, there are many crucial proteins involved in the reproduction control program, especially in follicular development. In order to isolate differential proteins between mature and immature follicular fluid (FF) of yak, the FF from yak follicles with different sizes were sampled respectively, and two-dimensional gel electrophoresis (2-DE) of the proteins was...
متن کاملA Comparative Study of Serum and Follicular Fluid Leptin Concentrations among Explained Infertile, Unexplained Infertile and Fertile Women
Background The relationship between metabolism and reproduction has been always considered as an important topic in female endocrinology. It seems that leptin is one of the involved factors in infertility. Leptin, in addition to regulating body weight plays an important role in regulation of endocrine, reproductive and immune systems. The aim of this stduy is to compare serum and follicular flu...
متن کاملA Proteomic Analysis of Human Follicular Fluid: Comparison between Younger and Older Women with Normal FSH Levels
The follicular fluid (FF) is produced during folliculogenesis and contains a variety of proteins that play important roles in follicle development and oocyte maturation. Age-related infertility is usually considered as a problem that can be solved by assisted reproduction technology. Therefore, the identification of novel biomarkers that are linked to reproductive aging is the subject of this st...
متن کاملO-26: Effects of Recombinant-LH Supplementation on The Proteomic Profile of Follicular Fluid from Poor Responder Patients: Focus on Follicular Growth Factors and Oocyte Maturity Markers
Background Poor and fragmentary data was available regarding the effects of recombinant-LH (r-LH) in in-vitro granulosa and theca cells of human origin. No data was available from in vivo studies regarding the effects of r-LH supplementation on SCF,EGF,ERK-1/2 and AKT-1 pathways in the follicular fluid of older-poor-responder women undergoing IVF cycle. Evidence from in-vitro and animal studies...
متن کاملProteomic analysis of human follicular fluid associated with successful in vitro fertilization
BACKGROUND Human follicular fluid (HFF) provides a key environment for follicle development and oocyte maturation, and contributes to oocyte quality and in vitro fertilization (IVF) outcome. METHODS To better understand folliculogenesis in the ovary, a proteomic strategy based on dual reverse phase high performance liquid chromatography (RP-HPLC) coupled to matrix-assisted laser desorption/io...
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ژورنال
عنوان ژورنال: Clinical Proteomics
سال: 2015
ISSN: 1542-6416,1559-0275
DOI: 10.1186/s12014-015-9077-6